Function and Structure of MalA/MalA′, Iterative Halogenases for Late-Stage C–H Functionalization of Indole Alkaloids-Reference-Cited by-同舟云学术

Function and Structure of MalA/MalA′, Iterative Halogenases for Late-Stage C–H Functionalization of Indole Alkaloids

Published:2017-08-21 Issue:34 Volume:139 Page:12060-12068
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Fraley Amy E.,Garcia-Borràs Marc¹,Tripathi Ashootosh,Khare Dheeraj,Mercado-Marin Eduardo V.²,Tran Hong,Dan Qingyun,Webb Gabrielle P.,Watts Katharine R.³,Crews Phillip³^ORCID,Sarpong Richmond²^ORCID,Williams Robert M.⁴,Smith Janet L.,Houk K. N.¹^ORCID,Sherman David H.^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States

2. Department of Chemistry, University of California, Berkeley, California 94720, United States

3. Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, United States

4. Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States

Funder

National Institutes of Health

National Institute of General Medical Sciences

National Science Foundation

Hans W. Vahlteich Professorship

Margaret J. Hunter Professorship

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.7b06773

Reference40 articles.

1. Specific Enzymatic Halogenation-From the Discovery of Halogenated Enzymes to Their Applications In Vitro and In Vivo

2. Tryptophan 7-Halogenase (PrnA) Structure Suggests a Mechanism for Regioselective Chlorination

3. Chlorination by a Long-Lived Intermediate in the Mechanism of Flavin-Dependent Halogenases,

4. A Novel Fungal Flavin-Dependent Halogenase for Natural Product Biosynthesis

5. Identification of a Halogenase Involved in the Biosynthesis of Ochratoxin A in Aspergillus carbonarius

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