Total Syntheses of Disorazoles A1 and B1 and Full Structural Elucidation of Disorazole B1
Author:
Affiliation:
1. Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, Texas 77005, United States
Funder
Welch Foundation
Cancer Prevention and Research Institute of Texas
Government of Canada
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.7b09843
Reference34 articles.
1. Antibiotics from Gliding Bacteria, LIX. Disorazoles, Highly Cytotoxic Metabolites from the Sorangicin-Producing BacteriumSorangium Cellulosum, Strain So ce12
2. Antibiotics from gliding bacteria. No.62. Disorazol A, an Efflcient Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria.
3. The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation
4. Cellular Analysis of Disorazole C1 and Structure-Activity Relationship of Analogs of the Natural Product
5. Microtubule Binding and Disruption and Induction of Premature Senescence by Disorazole C1
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