Genetically Encoding an Electrophilic Amino Acid for Protein Stapling and Covalent Binding to Native Receptors
Author:
Affiliation:
1. The Jack H. Skirball Center for Chemical Biology and Proteomics and ‡Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, California 92037, United States
Funder
California Institute for Regenerative Medicine
National Institutes of Health
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/cb500453a
Reference32 articles.
1. Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
2. Genetically Encoded Chemical Probes in Cells Reveal the Binding Path of Urocortin-I to CRF Class B GPCR
3. Proximity-Enabled Protein Crosslinking through Genetically Encoding Haloalkane Unnatural Amino Acids
4. Analysis of accessible surface of residues in proteins
5. Intramolecular isopeptide bonds: protein crosslinks built for stress?
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