Design, Synthesis, Structure–Function Relationship, Bioconversion, and Pharmacokinetic Evaluation of Ertapenem Prodrugs-Reference-Cited by-同舟云学术

Design, Synthesis, Structure–Function Relationship, Bioconversion, and Pharmacokinetic Evaluation of Ertapenem Prodrugs

Published:2014-10-14 Issue:20 Volume:57 Page:8421-8444
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Singh Sheo B.¹,Rindgen Diane¹,Bradley Prudence¹,Suzuki Takao²,Wang Nengxue²,Wu Hao²,Zhang Basheng²,Wang Li²,Ji Chongmin²,Yu Hongshi²,Soll Richard M.²,Olsen David B.³,Meinke Peter T.¹,Nicoll-Griffith Deborah A.¹

Affiliation:

1. Merck Research Laboratories, Rahway, New Jersey 07065, United States

2. WuXi AppTec, 288 Fute Zhong Road, Shanghai 200131, People’s Republic of China

3. Merck Research Laboratories, West Point, Pennsylvania 19486, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500879a

Reference25 articles.

1. Comparative Review of the Carbapenems

2. In Vitro Activity of Tebipenem, a New Oral Carbapenem Antibiotic, against Penicillin-Nonsusceptible Streptococcus pneumoniae

3. Population Pharmacokinetics of Tebipenem Pivoxil (ME1211), a Novel Oral Carbapenem Antibiotic, in Pediatric Patients with Otolaryngological Infection or Pneumonia

4. Comparison of the Efficacies of Oral β-Lactams in Selection of Haemophilus influenzae Transformants with Mutated ftsI Genes

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