Synthesis and Properties of 2′-Deoxy-2′,4′-difluoroarabinose-Modified Nucleic Acids

Author:

Martínez-Montero Saúl1,Deleavey Glen F.1,Dierker-Viik Arden1,Lindovska Petra1,Ilina Tatiana2,Portella Guillem3,Orozco Modesto3,Parniak Michael A.2,González Carlos4,Damha Masad J.1

Affiliation:

1. Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada

2. Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, Pennsylvania 15219-3143, United States

3. Joint IRB−BSC program on Computational Biology, Institute for Research in Biomedicine, Barcelona Supercomputing Center, and Department of Biochemistry, University of Barcelona, Baldiri Reixac 10-12, 08028 Barcelona, Spain

4. Instituto de Química Física Rocasolano, CSIC, C/ Serrano 119, 28006 Madrid, Spain

Funder

National Institute of General Medical Sciences

National Institute of Allergy and Infectious Diseases

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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