Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display-Reference-Cited by-同舟云学术

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Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display

Published:2024-08-13 Issue:34 Volume:146 Page:24053-24060
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Lan Tong¹^ORCID,Peng Cheng¹,Yao Xiyuan¹^ORCID,Chan Rachel Shu Ting¹,Wei Tongyao¹,Rupanya Anuchit¹,Radakovic Aleksandar¹,Wang Sijie²,Chen Shiyu²^ORCID,Lovell Scott²,Snyder Scott A.¹^ORCID,Bogyo Matthew²³^ORCID,Dickinson Bryan C.¹⁴^ORCID

Affiliation:

1. Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States

2. Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States

3. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, United States

4. Chan Zuckerberg Biohub, Chicago, Illinois 60642, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.4c07851

Reference61 articles.

1. Advances in covalent drug discovery

2. The resurgence of covalent drugs

3. Targeting the cancer kinome through polypharmacology

4. Quantitative reactivity profiling predicts functional cysteines in proteomes

5. Proteome-wide covalent ligand discovery in native biological systems

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