Catalytic Metal Ion–Substrate Coordination during Nonenzymatic RNA Primer Extension-Reference-Cited by-同舟云学术

Catalytic Metal Ion–Substrate Coordination during Nonenzymatic RNA Primer Extension

Published:2024-04-05 Issue:15 Volume:146 Page:10632-10639
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Fang Ziyuan¹^ORCID,Pazienza Lydia T.²³,Zhang Jian¹,Tam Chun Pong²³,Szostak Jack W.¹^ORCID

Affiliation:

1. Department of Chemistry, Howard Hughes Medical Institute, The University of Chicago, Chicago, Illinois 60637, United States

2. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

3. Department of Molecular Biology and Center for Computational and Integrative Biology, Howard Hughes Medical Institute, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States

Funder

Howard Hughes Medical Institute

Division of Chemistry

Gordon and Betty Moore Foundation

Alfred P. Sloan Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.4c00323

Reference53 articles.

1. Template-Directed Synthesis with Adenosine-5′-phosphorimidazolide

2. Oligomerization of (guanosine 5′-phosphor)-2-methylimidazolide on poly(C)

3. Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues.

4. Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

5. Catalysis of internucleotide bond formation by divalent metal ions

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