1. The Bristol-Myers Squibb Pharmaceutical Research Institute, Process Research P.O. Box 4000, Princeton, New Jersey 08543; New Brunswick, New Jersey 08903; Regensburg, Germany; Process Technology, New Brunswick, New Jersey 08903; Pharmaceutics, New Brunswick, New Jersey 08903; Solid State Chemistry, Princeton, New Jersey 08543; Anti-infective Chemistry, 5 Research Parkway, Wallingford, Connecticut 06492, U.S.A.