Stepwise Ultra-pH-Sensitive Micelles Overcome a p<i>K</i><sub>a</sub> Barrier for Systemic Lymph Node Delivery-Reference-Cited by-同舟云学术

Stepwise Ultra-pH-Sensitive Micelles Overcome a pK_a Barrier for Systemic Lymph Node Delivery

Published:2024-06-20 Issue:26 Volume:18 Page:16632-16647
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Bennett Zachary T.¹²^ORCID,Huang Gang¹^ORCID,Dellinger Michael T.³⁴,Sumer Baran D.⁵,Gao Jinming¹²⁵⁶^ORCID

Affiliation:

1. Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

2. Department of Biomedical Engineering, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

3. Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

4. Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

5. Department of Otolaryngology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

6. Department of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

Funder

National Cancer Institute

University of Texas Southwestern Medical Center

Cancer Prevention and Research Institute of Texas

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.4c00876

Reference62 articles.

1. Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake

2. Programmable multistage drug delivery to lymph nodes

3. Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy

4. Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma

5. A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles