Nanoparticle-Conjugated Toll-Like Receptor 9 Agonists Improve the Potency, Durability, and Breadth of COVID-19 Vaccines

Author:

Ou Ben S.1ORCID,Baillet Julie2,Picece Vittoria C. T. M.23,Gale Emily C.4,Powell Abigail E.45ORCID,Saouaf Olivia M.2,Yan Jerry1,Nejatfard Anahita4ORCID,Lopez Hernandez Hector2,Appel Eric A.12567ORCID

Affiliation:

1. Department of Bioengineering, Stanford University, Stanford, California 94305, United States

2. Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States

3. Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich 8093, Switzerland

4. Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, United States

5. Stanford ChEM-H, Stanford University, Stanford, California 94305, United States

6. Department of Pediatrics - Endocrinology, Stanford University School of Medicine, Stanford, California 94305, United States

7. Woods Institute for the Environment, Stanford University, Stanford, California 94305, United States

Funder

Stanford Maternal and Child Health Research Institute

Goldman Sachs

Stanford Bio-X

Division of Graduate Education

Bill and Melinda Gates Foundation

American Cancer Society

Eastman Kodak

Publisher

American Chemical Society (ACS)

Reference95 articles.

1. WHO Global Vaccine Action Plan 2011–2020. https://www.who.int/publications/i/item/global-vaccine-action-plan-2011-2020 (accessed 09/01, 2022).

2. WHO Coronavirus (COVID-19) Dashboard. https://covid19.who.int/ (accessed 09/01, 2022).

3. Recent Advances in Subunit Vaccine Carriers

4. Key roles of adjuvants in modern vaccines

5. Vaccine Adjuvants: Putting Innate Immunity to Work

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