Donepezil Nanoemulsion Induces a Torpor-like State with Reduced Toxicity in Nonhibernating Xenopus laevis Tadpoles

Author:

Plaza Oliver Maria123,Gardner Erica1,Lin Tiffany1,Sheehan Katherine1,Sperry Megan M.1,Lightbown Shanda1,Martínez Manuel Ramsés1,del Campo Daniela1,Fotowat Haleh1,Lewandowski Michael1,Takeda Takako1,C. Pauer Alexander1,Kaushal Shruti1,Gnyawali Vaskar1,Lozano Maria V.23ORCID,Santander Ortega Manuel J.23,Novak Richard1,Super Michael1,Ingber Donald E.145ORCID

Affiliation:

1. Wyss Institute for Biologically Engineering at Harvard University, Boston, Massachusetts 02215, United States

2. Development and Evaluation of Nanodrugs (DEVANA) Group, Faculty of Pharmacy and Biomedicine Institute at University of Castilla-La Mancha, 02008 Albacete, Spain

3. Castilla-La Mancha Health Research Institute (IDISCAM), 02071 Albacete, Spain

4. Vascular Biology Program & Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, United States

5. Harvard John A. Paulson School of Engineering and Applied Sciences, Boston, Massachusetts 02134, United States

Funder

Universidad de Castilla-La Mancha

Defense Advanced Research Projects Agency

Ministerio de Ciencia, Innovaci?n y Universidades

Army Research Office

Ministerio de Ciencia e Innovaci?n

European Regional Development Fund

Junta de Comunidades de Castilla-La Mancha

Publisher

American Chemical Society (ACS)

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