Biomimetic Mineralized CRISPR/Cas RNA Nanoparticles for Efficient Tumor-Specific Multiplex Gene Editing
Author:
Affiliation:
1. School of Pharmaceutical Sciences, Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou University, Zhengzhou 450001, P. R. China
Funder
Science and Technology Innovation Talents in Universities of Henan Province
National Natural Science Foundation of China
Henan Province Fund for Cultivating Advantageous Disciplines
Publisher
American Chemical Society (ACS)
Subject
General Physics and Astronomy,General Engineering,General Materials Science
Link
https://pubs.acs.org/doi/pdf/10.1021/acsnano.3c04116
Reference67 articles.
1. Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy
2. Predicting the mutations generated by repair of Cas9-induced double-strand breaks
3. Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors
4. CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia
5. Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer
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