Injectable Nanocomposite Hydrogels Improve Intraperitoneal Co-delivery of Chemotherapeutics and Immune Checkpoint Inhibitors for Enhanced Peritoneal Metastasis Therapy

Author:

Liang Shu1,Xiao Lingyun123,Chen Tian1,Roa Paola4ORCID,Cocco Emiliano4,Peng Zhangwen1,Yu Liu1,Wu Meiying1ORCID,Liu Jie5,Zhao Xizhe6,Deng Wenbin1ORCID,Wang Xiongjun2,Zhao Chao78ORCID,Deng Yang1,Mai Yang1

Affiliation:

1. School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen 518000, China

2. Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China

3. Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University, Southern University of Science and Technology), Shenzhen 518020, China

4. Department of Biochemistry and Molecular Biology/Sylvester Comprehensive Cancer Center, University of Miami/Miller School of Medicine, Miami, Florida 33136, United States

5. ISCTE Business School, BRU-IUL, University Institute of Lisbon, Avenida das Armadas, Lisbon 1649-026, Portugal

6. Department of Chemistry, College of Staten Island, City University of New York, New York, New York 10314, United States

7. Department of Chemical and Biological Engineering, University of Alabama, Tuscaloosa, Alabama 35487, United States

8. Alabama Life Research Institute, University of Alabama, Tuscaloosa, Alabama 35487, United States

Funder

China Postdoctoral Science Foundation

Science, Technology and Innovation Commission of Shenzhen Municipality

Sylvester Comprehensive Cancer Center, University of Miami Health Systems

National Natural Science Foundation of China

University of Miami

Lung Cancer Research Foundation

Publisher

American Chemical Society (ACS)

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