Tetrahedral Framework Nuclear Acids Can Regulate Interleukin-17 Pathway to Alleviate Inflammation and Inhibit Heterotopic Ossification in Ankylosing Spondylitis

Author:

Wang Lihang12ORCID,Wang Yun3,Jiang Yang4,Chen Ming4,Li Zhuhai15,Wang Kai1,Luo Chunshan2,Ning Ning1,Zeng Jiancheng1,Zhou Zongke1ORCID,Song Yueming1,Yang Fan6,Huang Shi-shu1,Lin Yunfeng37ORCID

Affiliation:

1. Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37 GuoXue Road, Chengdu 610041, China

2. Department of Spine Surgery, Beijing Jishuitan Hospital Guizhou Hospital, No. 206 Sixian Road, Guiyang 550014, China

3. State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14. 3rd Sec, Ren Min Nan Road, Chengdu 610041, China

4. The Second Affiliated Hospital of Chengdu Medical College, 416 Nuclear Industry Hospital, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China

5. Department of Spine Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, No. 6 TaoYuan Road, Nanning 530016, China

6. The Brain Cognition & Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen 518055, China

7. Sichuan Provincial Engineering Research Center of Oral Biomaterials, Chengdu, Sichuan 610041, China

Funder

West China Hospital, Sichuan University

West China School of Stomatology, Sichuan University

National Key Research and Development Program of China

Sichuan Province Youth Science and Technology Innovation Team

Science and Technology Department of Sichuan Province

Guizhou Provincial Science and Technology Department

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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