C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes

Author:

Tavano Regina,Gabrielli Luca,Lubian Elisa,Fedeli Chiara,Visentin Silvia,Polverino De Laureto Patrizia,Arrigoni Giorgio,Geffner-Smith Alessandra,Chen Fangfang12,Simberg Dmitri1ORCID,Morgese Giulia3,Benetti Edmondo M.3ORCID,Wu Linping45,Moghimi Seyed Moein156ORCID,Mancin FabrizioORCID,Papini EmanueleORCID

Affiliation:

1. Translational Bio-Nanosciences Laboratory and Colorado Center for Nanomedicine and Nanosafety, The Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, 1250 East Mountview Boulevard, Aurora, Colorado 80045, United States

2. Department of Gastrointestinal Surgery, China-Japan Union Hospital, Jilin University, 126 Xiantai Street, Changchun, Jilin 130033, China

3. Department of Materials, ETH, Zurich CH-8093, Switzerland

4. Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China

5. School of Pharmacy, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom

6. Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom

Funder

Government of Guangdong Province

Universit? degli Studi di Padova

Guangzhou City

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

RiboBio Co, Ltd.

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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