A Long-Acting Lyotropic Liquid Crystalline Implant Promotes the Drainage of Macromolecules by Brain-Related Lymphatic System in Treating Aged Alzheimer’s Disease

Author:

Shan Xinyu1,Lu Yichao1,Luo Zhenyu1,Zhao Xiaoqi1,Pang Mei1,Yin Hang1,Guo Xuemeng1,Zhou Huanli1,Zhang Junlei1,Huang Jiaxin1,Shi Yingying1,Lou Jinfang1,Luo Lihua12,You Jian1342ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, P. R. China

2. Jinhua Institute of Zhejiang University, 498 Yiwu Street, Jinhua, Zhejiang 321299, P. R. China

3. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, 79 Qingchun Road, Shangcheng District, Hangzhou, Zhejiang 310006, P. R. China

4. The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, Zhejiang 310000, P. R. China

Funder

National Key Research and Development Program of China

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Reference47 articles.

1. Zeisel, J.; Bennett, K.; Fleming, R. World Alzheimer Report 2020: Design, Dignity, Dementia: Dementia-Related Design and the Built Environment; Alzheimer’s Disease International, 2020; Vol. 1, 248 pp.

2. Alzheimer disease

3. Ageing as a risk factor for neurodegenerative disease

4. Alzheimer's disease drug development pipeline: 2023

5. Cellular senescence and Alzheimer disease: the egg and the chicken scenario

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