Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions

Author:

Anchordoquy Thomas J.,Barenholz Yechezkel1,Boraschi Diana2,Chorny Michael3,Decuzzi Paolo4,Dobrovolskaia Marina A.5,Farhangrazi Z. Shadi67,Farrell Dorothy8,Gabizon Alberto9,Ghandehari Hamidreza10,Godin Biana11,La-Beck Ninh M.12,Ljubimova Julia13,Moghimi S. Moein14,Pagliaro Len15,Park Ji-Ho16ORCID,Peer Dan17,Ruoslahti Erkki18,Serkova Natalie J.,Simberg Dmitri

Affiliation:

1. Laboratory of Membrane and Liposome Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

2. Institute of Protein Biochemistry, National Research Council, 80131 Napoli, Italy

3. Department of Pediatrics, Perelman School of Medicine and the Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States

4. Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, 16163 Genoa, Italy

5. Nanotechnology Characterization Lab, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States

6. Biotrends International, Denver Technological Center, Greenwood Village, Colorado 80111, United States

7. University College, University of Denver, Denver, Colorado 80208, United States

8. Office of Cancer Nanotechnology Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States

9. Oncology Institute, Shaare Zedek Medical Center, and Hebrew University−School of Medicine, Jerusalem 9103102, Israel

10. Departments of Pharmaceutics, Pharmaceutical Chemistry and of Bioengineering, University of Utah, Salt Lake City, Utah 84112, United States

11. Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas 77030, United States

12. Departments of Immunotherapeutics and Biotechnology, School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, Texas 79601, United States

13. Nanomedicine Research Center, Departments of Neurosurgery and of Biomedical Sciences, Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States

14. School of Medicine, Pharmacy and Health, Durham University, Queen’s Campus, Stockton-On-Tees TS17 6BH, United Kingdom

15. Siva Therapeutics Inc., Austin, Texas 78759, United States

16. Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea

17. Departments of Cell Research and Immunology and of Materials Sciences and Engineering, Tel Aviv University, Tel Aviv 69978, Israel

18. Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, United States

Funder

National Institute of Biomedical Imaging and Bioengineering

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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