Nano-mechanical Immunoengineering: Nanoparticle Elasticity Reprograms Tumor-Associated Macrophages via Piezo1

Author:

Yang Zichen1,Zhao Yuge1,Zhang Xiaoyou1,Huang Li1,Wang Kun2,Sun Jiuyuan1,Chen Nana1,Yin Weimin1,Chen Shiyu1,Zhi Hui1,Xue Liangyi1,An Lulu1,Li Rongjie1,Dong Haiqing3ORCID,Xu Jinfu4,Li Yan1ORCID,Li Yongyong1ORCID

Affiliation:

1. Shanghai Skin Disease Hospital, the Institute for Biomedical Engineering & Nano Science, School of Medicine, Tongji University, Shanghai 200092, China

2. Department of Nuclear Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China

3. Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration, Ministry of Education, Tongji Hospital, the Institute for Biomedical Engineering & Nano Science, School of Medicine, Tongji University, Shanghai 200092, P. R. China

4. Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai 200092, China

Funder

Natural Science Foundation of Shanghai Municipality

Ministry of Science and Technology of the People's Republic of China

Fundamental Research Funds for the Central Universities

Shanghai Municipal Health Commission

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

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