Synchronization of Nanoparticle Sensitization and Radiosensitizing Chemotherapy through Cell Cycle Arrest Achieving Ultralow X-ray Dose Delivery to Pancreatic Tumors

Author:

Manoharan Divinah1,Chang Li-Chan2,Wang Liu-Chun1,Shan Yan-Shen23,Lin Forn-Chia4,Wu Lai-Chin5,Sheu Hwo-Shuenn5,Su Wen-Pin26ORCID,Yeh Chen-Sheng178ORCID

Affiliation:

1. Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan

2. Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan

3. Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan

4. Department of Radiation Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan

5. National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan

6. Departments of Oncology and Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan

7. Center of Applied Nanomedicine, National Cheng Kung University, Tainan 704, Taiwan

8. Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan

Funder

National Cheng Kung University Hospital

Ministry of Science and Technology, Taiwan

Chi-Mei Medical Center

Ministry of Education, TAIWAN

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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