Freeze-Drying of tert-Butyl Alcohol/Water Cosolvent Systems: Effects of Formulation and Process Variables on Residual Solvents

Author:

Wittaya-areekul Sakchai,Nail Steven L.

Publisher

American Geophysical Union (AGU)

Subject

Pharmaceutical Science

Reference7 articles.

1. Thermal analysis of the tertiary butyl alcohol–water system and its implications on freeze- drying;Kasraian;Pharm. Res.,1995

2. The effect of tertiary butyl alcohol on the resistance of the dry product layer during primary drying;Kasraian;Pharm. Res.,1995

3. Statistical procedures for optimizing the freeze-drying of a model drug in tert-butyl alcohol:water mixtures;Baldi;Eur. J. Pharm. Biopharm.,1994

4. Volatile solvents for drying and microbial kill in the final container: A proposal and a review, with emphasis on tert-butyl alcohol;Olsen;Pharm. Eng.,1997

5. (Solid+liquid) phase equilibria and solid-hydrate formation in water+methyl, +ethyl, +isopropyl, and+tertiary butyl alcohols;Ott;J. Chem. Thermodyn.,1979

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