Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization
Author:
Affiliation:
1. Departments of Chemical and Screening Sciences, Inflammation, and Drug Safety and Metabolism, Wyeth Research, 200 CambridgePark Drive, Cambridge, Massachusetts 02140, and Organix Inc., 240 Salem Street, Woburn, Massachusetts 01801
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0507882
Reference112 articles.
1. The Coxibs, Selective Inhibitors of Cyclooxygenase-2
2. Molecular mechanisms of nociception
3. Neuronal Plasticity: Increasing the Gain in Pain
4. The ligand that came from within
5. Lysophospholipids--Receptor Revelations
Cited by 72 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. N,N-Disubstituted 4-Sulfamoylbenzoic Acid Derivatives as Inhibitors of Cytosolic Phospholipase A2α: Synthesis, Aqueous Solubility, and Activity in a Vesicle and a Whole Blood Assay;Medicinal Chemistry;2024-12
2. P,N‐Coordinating Ylide‐Functionalized Phosphines (NYPhos): A Ligand Platform for the Selective Monoarylation of Small Nucleophiles;Angewandte Chemie International Edition;2024-08-02
3. P,N‐koordinierende Ylid‐funktionalisierte Phosphane (NYPhos): Eine Ligandenplattform für die selektive Monoarylierung kleiner Nukleophile;Angewandte Chemie;2024-08-02
4. 3D‐QSAR pharmacophore modeling, virtual screening, molecular docking, MD simulations, in vitro and in vivo studies to identify potential anti‐hyperplasia drugs;Biotechnology Journal;2024-02
5. 1-Benzylindoles as inhibitors of cytosolic phospholipase A2α: synthesis, biological activity, aqueous solubility, and cell permeability;RSC Medicinal Chemistry;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3