CoMFA-Based Prediction of Agonist Affinities at Recombinant Wild Type versus Serine to Alanine Point Mutated D2 Dopamine Receptors-Reference-Cited by-同舟云学术

CoMFA-Based Prediction of Agonist Affinities at Recombinant Wild Type versus Serine to Alanine Point Mutated D2 Dopamine Receptors

Published:2000-07-18 Issue:16 Volume:43 Page:3005-3019
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wilcox Richard E.¹,Huang Wen-Hsin¹,Brusniak Mi-Youn Kim¹,Wilcox David M.¹,Pearlman Robert S.¹,Teeter Martha M.¹,DuRand Curtiss J.¹,Wiens Brenda L.¹,Neve Kim A.¹

Affiliation:

1. Molecular Pharmacology Laboratory and Laboratory for Molecular Graphics and Theoretical Modeling, College of Pharmacy, and Institute for Neuroscience, University of Texas, Austin, Texas 78712, Laboratory of Protein Modeling, Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02167, Psychiatry Service, Department of Veterans Affairs Medical Center, Bedford, Massachusetts 01730, and Medical Research Service, Department of Veterans Affairs Medical Center, Portland, Oregon 97201

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990526y

Reference34 articles.

1. Wilcox, R. E.; Gonzales, R. A.; Miller, J. D.Introductiontoneurotransmitters,receptors,signaltransduction,andsecondmessengers, 2nd ed.; C. B. Nemeroff, A. F. S., Ed.; American Psychiatric Press: 1998; pp 3−36.

2. Neurochemistry and Neuroendocrinology of Schizophrenia: A Selective Review

3. Molecular biology of dopamine receptors

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