A Post-PKS Oxidation of the Amphotericin B Skeleton Predicted to be Critical for Channel Formation Is Not Required for Potent Antifungal Activity
Author:
Affiliation:
1. Roger Adams Laboratory, Department of Chemistry, University of Illinois at UrbanaChampaign, Urbana, Illinois 61801
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja075739o
Reference48 articles.
1. Antifungal drug resistance of pathogenic fungi
2. The Interaction of Polyene Antibiotics with Thin Lipid Membranes
3. The Ion Permeability Induced in Thin Lipid Membranes by the Polyene Antibiotics Nystatin and Amphotericin B
4. Single ionic channels induced in lipid bilayers by polyene antibiotics amphotericin B and nystatine
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