Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor γ-Reference-Cited by-同舟云学术

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Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor γ

Published:2013-02-06 Issue:4 Volume:56 Page:1535-1543
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

de Groot Jens C.¹,Weidner Christopher²,Krausze Joern¹,Kawamoto Ken³,Schroeder Frank C.³,Sauer Sascha²,Büssow Konrad¹

Affiliation:

1. Department of Molecular Structural Biology, Helmholtz Centre for Infection Research, 38214 Braunschweig, Germany

2. Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany

3. Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3013272

Reference26 articles.

1. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

2. The Mechanisms of Action of PPARs

3. Fat and Beyond: The Diverse Biology of PPARγ

4. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors and

5. Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors

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1. Molecules and targets of antidiabetic interest;Phytomedicine Plus;2024-02

2. PPARα/γ-Targeting Amorfrutin Phytocannabinoids from Aerial Parts of Glycyrrhiza foetida;Journal of Natural Products;2023-11-08

3. Natural products as novel anti-obesity agents: insights into mechanisms of action and potential for therapeutic management;Frontiers in Pharmacology;2023-06-20

4. Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition;Biomolecules;2023-04-19

5. Peptide Helix-Y12 as Potential Effector for Peroxisome Proliferator-Activated Receptors;PPAR Research;2023-04-15

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