Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2

Author:

Wang Jie1,Takyi Nathania A.2ORCID,Hsiao Yun-Chung3,Tang Qi1,Chen Yi-Tzai1,Liu Chih-Wei3ORCID,Ma Jian1,Qi Rui1,Bian Ke1ORCID,Peng Zhiyuan1,Essigmann John M.4ORCID,Lu Kun3ORCID,Wetmore Stacey D.2ORCID,Li Deyu1ORCID

Affiliation:

1. Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, United States

2. Department of Chemistry and Biochemistry, University of Lethbridge, 4401 University Drive West, Lethbridge, Alberta T1K 3M4, Canada

3. Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

4. Departments of Biological Engineering, Chemistry, and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

Funder

National Institute of Environmental Health Sciences

National Cancer Institute

Canada Research Chairs

University of Lethbridge

Natural Sciences and Engineering Research Council of Canada

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

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