Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole: Evidence for Complex Heme Interactions-Reference-Cited by-同舟云学术

Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole: Evidence for Complex Heme Interactions

Published:2006-11-24 Issue:12 Volume:19 Page:1650-1659
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Hutzler J. Matthew¹,Melton Roger J.¹,Rumsey Jeanne M.¹,Schnute Mark E.¹,Locuson Charles W.¹,Wienkers Larry C.¹

Affiliation:

1. Pharmacokinetics, Dynamics and Metabolism (PDM), Department of Medicinal Chemistry, Pfizer Global Research and Development, 700 Chesterfield Parkway West T3A, Chesterfield, Missouri 63017, and Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx060198m

Reference51 articles.

1. Mechanistic Studies with Potent and Selective Inducible Nitric-oxide Synthase Dimerization Inhibitors

2. The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

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