From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells-Reference-Cited by-同舟云学术

From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells

Published:2009-03-16 Issue:7 Volume:52 Page:1853-1863
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gaisina Irina N.¹,Gallier Franck¹,Ougolkov Andrei V.¹,Kim Ki H.¹,Kurome Toru¹,Guo Songpo¹,Holzle Denise¹,Luchini Doris N.¹,Blond Sylvie Y.¹,Billadeau Daniel D.¹,Kozikowski Alan P.¹

Affiliation:

1. Drug Discovery Program, College of Pharmacy, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, Department of Medicinal Chemistry and Pharmacognosy and the Center for Pharmaceutical Biotechnology, University of Illinois at Chicago, 900 South Ashland, Chicago, Illinois 60607, and College of Medicine, Department of Immunology and Division of Oncology Research, Mayo Clinic, 13-42 Guggenheim, 200 First Street SW, Rochester,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801317h

Reference26 articles.

1. Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle

2. Molecular cloning and expression of glycogen synthase kinase-3/factor A.

3. GSK3 inhibitors: development and therapeutic potential

4. GSK3, a master switch regulating cell-fate specification and tumorigenesis

5. Insulin-like Growth Factor I Triggers Nuclear Accumulation of Cyclin D1 in MCF-7S Breast Cancer Cells

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