Synthesis and Biological Activity of Nitro Heterocycles Analogous to Megazol, a Trypanocidal Lead-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of Nitro Heterocycles Analogous to Megazol, a Trypanocidal Lead

Published:2003-01-01 Issue:3 Volume:46 Page:427-440
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chauvière Gérard¹,Bouteille Bernard¹,Enanga Bertin¹,de Albuquerque Cristina¹,Croft Simon L.¹,Dumas Michel¹,Périé Jacques¹

Affiliation:

1. Groupe de Chimie Organique Biologique, Laboratoire de Synthèse et Physicochimie de Molécules d'Intérêt Biologique, Université Paul Sabatier, UMR CNRS 5068, 31062 Toulouse, France, Faculté de Médecine, Institut d'Epidémiologie Neurologique et de Neurologie Tropicale (EA 3174), Limoges, France, Faculty of Pharmacy, University of Sao Paulo, Brazil, and Department of Infections and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm021030a

Reference35 articles.

1. The challenge of Chagas' disease chemotherapy: An update of drugs assayed against Trypanosoma cruzi

2. A nitroimidazole-thiadiazole derivative with curative action in experimentalTrypanosoma cruziinfections

3. Effect of megazol on Trypanosoma brucei brucei acute and subacute infections in Swiss mice

Cited by 134 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring Acyl Thiotriazinoindole Based Pharmacophores: Design, Synthesis, and SAR Studies with Molecular Docking and Biological Activity Profiling against Urease, α-amylase, α-glucosidase, Antimicrobial, and Antioxidant Targets;The Protein Journal;2024-09-02

2. Thiadiazoles;S-Heterocycles;2024-07-24

3. Synthesis, Properties, and Biological Applications of 1,3,4-Thiadiazoles;S-Heterocycles;2024-07-24

4. Synthesis, cytotoxicity and antioxidant activity of new conjugates of N-acetyl-d-glucosamine with α-aminophosphonates;Carbohydrate Research;2024-07

5. Synthesis and in-silico studies of 4-(5-(2-(4-(5-aryl-1,2,4-thiadiazol-3-yl)phenyl)-1H-imidazol-4-yl)-1,3,4-thiadiazol-2-yl)pyridines;Results in Chemistry;2024-01