A Potent Aldose Reductase Inhibitor, (2S,4S)-6-Fluoro-2‘,5‘-dioxospiro[chroman-4,4‘-imidazolidine]-2-carboxamide (Fidarestat): Its Absolute Configuration and Interactions with the Aldose Reductase by X-ray Crystallography-Reference-Cited by-同舟云学术

A Potent Aldose Reductase Inhibitor, (2S,4S)-6-Fluoro-2‘,5‘-dioxospiro[chroman-4,4‘-imidazolidine]-2-carboxamide (Fidarestat): Its Absolute Configuration and Interactions with the Aldose Reductase by X-ray Crystallography

Published:2000-05-18 Issue:12 Volume:43 Page:2479-2483
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Oka Mitsuru¹,Matsumoto Yukiharu¹,Sugiyama Shigeru¹,Tsuruta Nobuaki¹,Matsushima Masaaki¹

Affiliation:

1. Rational Drug Design Laboratories, 4-1-1, Misato, Matsukawa-machi, Fukushima 960-1242, Japan, Sanwa Kagaku Kenkyusyo Company, Ltd., 363, Shiosaki, Hokusei-cho, Inabe-gun, Mie 511-0406, Japan, and Maruwa Food Industry Company, Ltd., 170, Tsutsuji-cho, Yamatokoriyama, Nara 639-1123, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990502r

Reference28 articles.

1. The involvement of aldose reductase in diabetic complications

2. Synthesis, absolute configuration and conformation of the aldose reductase inhibitor sorbinil

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