Catechol:  A Minimal Scaffold for Non-Peptide Peptidomimetics of the i + 1 and i + 2 Positions of the β-Turn of Somatostatin

Author:

Mowery Brendan P.1,Prasad Vidya1,Kenesky Craig S.1,Angeles Angie R.1,Taylor Laurie L.1,Feng Jin-Jye1,Chen Wen-Long1,Lin Atsui1,Cheng Fong-Chi1,Smith Amos B.1,Hirschmann Ralph1

Affiliation:

1. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, MDS Pharma Services, 22011 30th Drive SE, Bothell, Washington 98021, and MDS Pharma ServicesTaiwan Ltd., 158 Li-Teh Road, Peitou, Taipei, Taiwan 112, ROC

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference30 articles.

1. Conformationally restricted bicyclic analogs of somatostatin.

2. Biologic and immunologic activities and applications of somatostatin analogs

3. A potent cyclic hexapeptide analogue of somatostatin

4. (a) Freidinger, R. M.; Veber, D. F.Conformationally Directed DrugDesign, Peptides and Nucleic Acids as Templates of Targets; Vida, J., Gordon, M., Eds.; American Chemical Society:  Washington, DC, 1984; p 169.

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