Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate, Part 1:  Improving the Pharmacokinetic Profile Using the Structure−Property Relationship

Author:

Bonfanti Jean-François1,Doublet Frédéric1,Fortin Jérôme1,Lacrampe Jean1,Guillemont Jérôme1,Muller Philippe1,Queguiner Laurence1,Arnoult Eric1,Gevers Tom1,Janssens Peggy1,Szel Heidi1,Willebrords Rudy1,Timmerman Philip1,Wuyts Koen1,Janssens Frans1,Sommen Cois1,Wigerinck Piet1,Andries Koen1

Affiliation:

1. Johnson & Johnson Pharmaceutical Research and Development, Medicinal Chemistry Department, Campus de Maigremont BP315, F-27106 Val de Reuil, France, Johnson & Johnson Pharmaceutical Research and Development, Antimicrobial Research Department, Turnhoutseweg 30, B-2340 Beerse, Belgium, Johnson & Johnson Pharmaceutical Research and Development, ADME-Tox & Bioanalysis Department, Turnhoutseweg 30, B-2340 Beerse, Belgium, Johnson & Johnson Pharmaceutical Research and Development, Medicinal Chemistry...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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