From Target to Drug: Generative Modeling for the Multimodal Structure-Based Ligand Design-Reference-Cited by-同舟云学术

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From Target to Drug: Generative Modeling for the Multimodal Structure-Based Ligand Design

Published:2019-08-22 Issue:10 Volume:16 Page:4282-4291
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Skalic Miha¹^ORCID,Sabbadin Davide¹,Sattarov Boris¹,Sciabola Simone²,De Fabritiis Gianni¹³⁴^ORCID

Affiliation:

1. Computational Science Laboratory, Universitat Pompeu Fabra, Barcelona Biomedical Research Park (PRBB), C Dr Aiguader 88, 08003 Barcelona, Spain

2. Biogen Chemistry and Molecular Therapeutics, 115 Broadway Street, Cambridge, Massachusetts 02142, United States

3. Acellera, Barcelona Biomedical Research Park (PRBB), C Dr. Aiguader 88, 08003 Barcelona, Spain

4. Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluis Companys 23, 08010 Barcelona, Spain

Funder

Consejo Superior de Investigaciones Cient?ficas

Horizon 2020 Framework Programme

Acellera ltd.

FEDER

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00634

Reference65 articles.

1. The Process of Structure-Based Drug Design

2. Software for molecular docking: a review

3. The next level in chemical space navigation: going far beyond enumerable compound libraries

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