Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling-Reference-Cited by-同舟云学术

Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling

Published:2021-12-23 Issue:2 Volume:19 Page:508-519
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Mahapatra Sujata¹²,Polimeni Marco³^ORCID,Gentiluomo Lorenzo⁴⁵,Roessner Dierk⁴,Frieß Wolfgang⁵,Peters Günther H. J.²^ORCID,Streicher Werner W.¹,Lund Mikael³⁶^ORCID,Harris Pernille²^ORCID

Affiliation:

1. Novozymes A/S, Biologiens Vej 2, 2800 Kgs. Lyngby, Denmark

2. Department of Chemistry, Technical University of Denmark, Kemitorvet Building 207, 2800 Kgs. Lyngby, Denmark

3. Division of Theoretical Chemistry, Department of Chemistry, Lund University, Naturvetarvägen 14, 223 62 Lund, Sweden

4. Wyatt Technology Europe GmbH, Hochstrasse 12a, 56307 Dernbach, Germany

5. Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig Maximilians-Universität München, Butenandtstrasse 5, 81377 Munich, Germany

6. Advanced X-ray and Neutron Science (LINXS), Lund University, Scheelevägen 19, 22370 Lund, Sweden

Funder

European Commission

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00627

Reference57 articles.

1. Therapeutic antibodies: successes, limitations and hopes for the future

2. Monoclonal antibodies: versatile platforms for cancer immunotherapy