Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes-Reference-Cited by-同舟云学术

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

Author:

Wegler Christine¹²^ORCID,Matsson Pär¹^ORCID,Krogstad Veronica³,Urdzik Jozef⁴,Christensen Hege³,Andersson Tommy B.²,Artursson Per⁵^ORCID

Affiliation:

1. Department of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden

2. DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden

3. Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, 0315 Oslo, Norway

4. Department of Surgical Sciences, Uppsala University, 751 85 Uppsala, Sweden

5. Department of Pharmacy and Science for Life Laboratory, Uppsala University, 752 37 Uppsala, Sweden

Funder

Vetenskapsr?det

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

Reference87 articles.

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