Characterizing Silicone Oil-Induced Protein Aggregation with Stimulated Raman Scattering Imaging-Reference-Cited by-同舟云学术

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Characterizing Silicone Oil-Induced Protein Aggregation with Stimulated Raman Scattering Imaging

Published:2023-06-29 Issue:8 Volume:20 Page:4268-4276
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Wong Brian¹,Zhao Xi²³,Su Yongchao²^ORCID,Ouyang Hanlin²,Rhodes Timothy²,Xu Wei²,Xi Hanmi²,Fu Dan¹^ORCID

Affiliation:

1. Department of Chemistry, University of Washington, Seattle, Washington 98195, United States

2. Analytical Enabling Capabilities, Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

3. Sterile and Specialty Products, Pharmaceutical Sciences & Clinical Supply, Merck & Co., Inc., Rahway, New Jersey 07065, United States

Funder

Merck Sharp and Dohme

Eli Lilly and Company

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00391

Reference45 articles.

1. Protein therapeutics: a summary and pharmacological classification

2. Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models

3. Immunogenicity of Therapeutic Protein Aggregates

4. Aggregation of protein therapeutics enhances their immunogenicity: causes and mitigation strategies

5. Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization

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1. Label-Free Screening of Drug-Induced Liver Injury Using Stimulated Raman Scattering Microscopy and Spectral Phasor Analysis;Analytical Chemistry;2024-06-18

2. Innovative Approaches for Drug Discovery: Quantifying Drug Distribution and Response with Raman Imaging;Analytical Chemistry;2024-04-16

3. Spectral fingerprinting of cellular lipid droplets using stimulated Raman scattering microscopy and chemometric analysis;The Analyst;2024

4. New insights into lipid and fatty acid metabolism from Raman spectroscopy;The Analyst;2024

5. Design of a Reciprocal Injection Device for Stability Studies of Parenteral Biological Drug Products;Journal of Pharmaceutical Sciences;2023-12

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