Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing-Reference-Cited by-同舟云学术

Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing

Published:2023-07-18 Issue:8 Volume:20 Page:4285-4296
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

O’Brien Laramy Matthew N.¹^ORCID,Costa Antonio P.²,Cebrero Yareli Maciel¹,Joseph Johnson²,Sarode Apoorva¹^ORCID,Zang Nanzhi¹,Kim Lee Joon³,Hofmann Kate¹,Wang Shirley¹^ORCID,Goyon Alexandre¹,Koenig Stefan G.¹^ORCID,Hammel Michal³^ORCID,Hura Greg L.³⁴

Affiliation:

1. Genentech, Inc., Genentech Research and Early Development, Synthetic Molecule Pharmaceutical Sciences, 1 DNA Way, South San Francisco, California 94060, United States

2. DIANT Pharma, Inc., 130 Utopia Road, Manchester, Connecticut 06042, United States

3. Lawrence Berkeley National Laboratory, Molecular Biophysics and Integrated Bioimaging Division, Berkeley, California 94720, United States

4. University of California Santa Cruz, Department of Chemistry and Biochemistry, Santa Cruz, California 95064, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00390

Reference43 articles.

1. Lipid Nanoparticle Systems for Enabling Gene Therapies

2. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis