Improved Predictions of Drug–Drug Interactions Mediated by Time-Dependent Inhibition of CYP3A
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, Pennsylvania 19140, United States
Funder
U.S. Department of Health and Human Services
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00129
Reference134 articles.
1. Application of mechanism-based CYP inhibition for predicting drug–drug interactions
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4. Cytochrome P450 Enzymes Mechanism Based Inhibitors: Common Sub-Structures and Reactivity
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