IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies
Author:
Affiliation:
1. Bioneer-FARMA, Department of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark
2. Section of Pharmaceutical Design and Drug Delivery, Department of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark
Funder
Ministeriet for Forskning, Innovation og Videregående Uddannelser
Lundbeckfonden
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00874
Reference71 articles.
1. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
2. Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.
3. ABC multidrug transporters: structure, function and role in chemoresistance
4. Expression of MDR1 (Multidrug Resistance) Gene and Its Protein in Normal Human Kidney
5. Expression of a multidrug-resistance gene in human tumors and tissues.
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