In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging

Author:

Verdurand Mathieu1,Levigoureux Elise12ORCID,Zeinyeh Wael1,Berthier Laurent3,Mendjel-Herda Meriem1,Cadarossanesaib Florence4,Bouillot Caroline4,Iecker Thibault4,Terreux Raphaël3,Lancelot Sophie12,Chauveau Fabien1,Billard Thierry45ORCID,Zimmer Luc124

Affiliation:

1. Université de Lyon, Université Claude Bernard Lyon 1, Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, Lyon 69361, France

2. Hospices Civils de Lyon, Lyon 69361, France

3. Université de Lyon, Université Claude Bernard Lyon 1, Institute of Biology and Chemistry of Proteins, CNRS UMR5305, Lyon 69361, France

4. CERMEP-Imaging Platform, Bron 69677, France

5. Université de Lyon, Université Claude Bernard Lyon 1, Institute of Chemistry and Biochemistry, CNRS UMR5246, Villeurbanne 69100, France

Funder

Agence Nationale de la Recherche

Fondation Plan Alzheimer

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference53 articles.

1. Thinking laterally about neurodegenerative proteinopathies

2. Intracellular Dynamics of Synucleins

3. New Tracers and New Perspectives for Molecular Imaging in Lewy Body Diseases

4. Diagnosis and management of dementia with Lewy bodies

5. M J Fox Foundation, ALPHA–SYNUCLEIN IMAGING PRIZE. https://www.michaeljfox.org/research/imaging-prize.html?navid=alpha-syn-image-prize (2018).

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