A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease-Reference-Cited by-同舟云学术

A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease

Published:2016-02-16 Issue:3 Volume:13 Page:863-872
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Pritchard Manon F.¹,Powell Lydia C.¹,Menzies Georgina E.,Lewis Paul D.,Hawkins Karl,Wright Chris,Doull Iolo²,Walsh Timothy R.³,Onsøyen Edvar⁴,Dessen Arne⁴,Myrvold Rolf⁴,Rye Philip D.⁴,Myrset Astrid H.⁴,Stevens Howard N. E.⁵,Hodges Lee A.⁵,MacGregor Gordon⁶,Neilly James B.⁷,Hill Katja E.¹,Thomas David W.¹

Affiliation:

1. Advanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, U.K.

2. Respiratory/Cystic Fibrosis Unit, Children’s Hospital for Wales, Cardiff CF14 4XW, U.K.

3. Medical Microbiology, School of Medicine, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4EP, U.K.

4. AlgiPharma AS, Sandvika 1337, Norway

5. Bio-Images Drug Delivery Ltd., Glasgow G4 0SF, U.K.

6. Gartnavel Hospital, Glasgow G12 0YN, U.K.

7. Glasgow Royal Infirmary, Glasgow G4 0ET, U.K.

Funder

European Commission

Norges Forskningsr?d

Cystic Fibrosis Foundation

European Social Fund

AlgiPharma AS

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00794

Reference45 articles.

1. The Global Burden of Respiratory Disease

2. New model tackles sticky problem of getting drugs past mucus

3. Elastic contributions dominate the viscoelastic properties of sputum from cystic fibrosis patients

4. Mucin structure, aggregation, physiological functions and biomedical applications

5. Mucus structure and properties in cystic fibrosis

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