Effect of Signal Interference from Dosing Excipients on Pharmacokinetic Screening of Drug Candidates by Liquid Chromatography/Mass Spectrometry-Reference-Cited by-同舟云学术

Effect of Signal Interference from Dosing Excipients on Pharmacokinetic Screening of Drug Candidates by Liquid Chromatography/Mass Spectrometry

Published:2002-11-15 Issue:24 Volume:74 Page:6305-6313
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Tong Xinchun S.¹,Wang Junying¹,Zheng Song¹,Pivnichny James V.¹,Griffin Patrick R.¹,Shen Xiaolan¹,Donnelly Marcie¹,Vakerich Ken¹,Nunes Chris¹,Fenyk-Melody Judy¹

Affiliation:

1. Basic Chemistry and Comparative Medicine, Merck Research Laboratory, Merck & Co., Inc., P.O. Box 2000, RY800-B205, Rahway, New Jersey 07065

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac025988p

Reference28 articles.

1. Quantification of a potent 5-HT2a antagonist and an active metabolite in rat plasma and brain microdialysate by liquid chromatography-tandem mass spectrometry

2. Characterization of a technique for rapid pharmacokinetic studies of multiple co-eluting compounds by LC/MS/MS

3. High-speed liquid chromatography/tandem mass spectrometry for the determination of drugs in biological samples

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