A Dimeric Sesquiterpenoid from a Malaysian Meiogyne as a New Inhibitor of Bcl-xL/BakBH3 Domain Peptide Interaction-Reference-Cited by-同舟云学术

A Dimeric Sesquiterpenoid from a Malaysian Meiogyne as a New Inhibitor of Bcl-xL/BakBH3 Domain Peptide Interaction

Published:2009-01-22 Issue:3 Volume:72 Page:480-483
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Litaudon Marc¹,Bousserouel Hadjira¹,Awang Khalijah¹,Nosjean Olivier¹,Martin Marie-Thérèse¹,Dau Marie Elise Tran Huu¹,Hadi Hamid A¹,Boutin Jean A.¹,Sévenet Thierry¹,Guéritte Françoise¹

Affiliation:

1. Institut de Chimie des Substances Naturelles, 1 Avenue de la Terrasse, UPR2301, CNRS, 91198 Gif-sur-Yvette, France, Department of Chemistry, University of Malaya, Pantai Valley, Kuala Lumpur, Malaysia, and Institut de Recherche Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np8006292

Reference14 articles.

1. Bcl-xL Is Overexpressed in Hormone-Resistant Prostate Cancer and Promotes Survival of LNCaP Cells via Interaction with Proapoptotic Bak

2. Expression of bcl-xL can confer a multidrug resistance phenotype

3. Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

4. Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

5. Dr. P. J. A.Kessler (National Herbarium of the Netherlands, Leiden), personal communication.

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