The Dawn of Metal-Oxo Clusters as Artificial Proteases: From Discovery to the Present and Beyond
Author:
Affiliation:
1. Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium
Funder
KU Leuven
Fonds Wetenschappelijk Onderzoek
Horizon 2020 Framework Programme
Publisher
American Chemical Society (ACS)
Subject
General Medicine,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.0c00666
Reference64 articles.
1. Molecular Insight from DFT Computations and Kinetic Measurements into the Steric Factors Influencing Peptide Bond Hydrolysis Catalyzed by a Dimeric Zr(IV)-Substituted Keggin Type Polyoxometalate
2. Chemical Mimics of Aspartate‐Directed Proteases: Predictive and Strictly Specific Hydrolysis of a Globular Protein at Asp−X Sequence Promoted by Polyoxometalate Complexes Rationalized by a Combined Experimental and Theoretical Approach
3. Protein‐Assisted Formation and Stabilization of Catalytically Active Polyoxometalate Species
4. Superactivity of MOF-808 toward Peptide Bond Hydrolysis
5. Protein Analysis by Shotgun/Bottom-up Proteomics
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