Identification of Selective Norbornane-Type Aspartate Analogue Inhibitors of the Glutamate Transporter 1 (GLT-1) from the Chemical Universe Generated Database (GDB)-Reference-Cited by-同舟云学术

Identification of Selective Norbornane-Type Aspartate Analogue Inhibitors of the Glutamate Transporter 1 (GLT-1) from the Chemical Universe Generated Database (GDB)

Published:2010-09-02 Issue:19 Volume:53 Page:7236-7250
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Luethi Erika¹,Nguyen Kong T.¹,Bürzle Marc²,Blum Lorenz C.¹,Suzuki Yoshiro²,Hediger Matthias²³,Reymond Jean-Louis¹³

Affiliation:

1. Department of Chemistry and Biochemistry, University of Berne, Freiestrasse 3, 3012 Berne, Switzerland

2. Institute of Biochemistry and Molecular Medicine, University of Berne, Bühlstrasse 28, 3012 Berne, Switzerland

3. Swiss National Center of Competence in Research, NCCR-TransCure, University of Berne, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100959g

Reference46 articles.

1. Druggable Targets and Targeted Drugs: Enhancing the Development of New Therapeutics

2. Virtual Exploration of the Small-Molecule Chemical Universe below 160 Daltons

3. Virtual Exploration of the Chemical Universe up to 11 Atoms of C, N, O, F: Assembly of 26.4 Million Structures (110.9 Million Stereoisomers) and Analysis for New Ring Systems, Stereochemistry, Physicochemical Properties, Compound Classes, and Drug Discovery

4. 970 Million Druglike Small Molecules for Virtual Screening in the Chemical Universe Database GDB-13

5. Chemical space as a source for new drugs

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bioactive Analysis of Antibacterial Efficacy and Antioxidant Potential of Aloe barbadensis Miller Leaf Extracts and Exploration of Secondary Metabolites Using GC–MS Profiling;Applied Biochemistry and Biotechnology;2023-05-15

2. Computer-aided drug design: An overview;Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development;2023

3. Generative Models for De Novo Drug Design;Journal of Medicinal Chemistry;2021-09-17

4. Logistic regression and random forest unveil key molecular descriptors of druglikeness;Chem-Bio Informatics Journal;2021-09-08

5. Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library;ChemMedChem;2021-08-31