Nanoreactors with Cascade Catalytic Activity Reprogram the Tumor Microenvironment for Enhanced Immunotherapy by Synchronously Regulating Treg and Macrophage Cells

Author:

Fu Yuhan1,Zhang Yuanyuan2,Zhang Yujie2,Li Runqing3,Yang Mei4,Bai Ting5,Zheng Xiaoliang6,Huang Dongsheng1,Zhang Mingzhen27ORCID,Tu Kangsheng7ORCID,Xu Qiuran1,Liu Xin1

Affiliation:

1. Zhejiang Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang 310014, China

2. School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

3. Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

4. Key Laboratory of Enhanced Recovery after Surgery of Intergrated Chinese and Western Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

5. Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

6. School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, Zhejiang 310053, China

7. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

Funder

Natural Science Foundation of Zhejiang Province

National Health Commission-Major Health Science and Technology Program of Zhejiang Province

Publisher

American Chemical Society (ACS)

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