Exploratory Investigation of Zinc-Modified Borosilicate Bioactive Glass: A New Methodology for Its Biocompatibility, Immunoregulation, and Pro-Angiogenic Property Evaluation

Author:

Zhang Liyan12,Huang Jing3,Li Li34,Zhang Hao15,Li Shuaijie15,Chai Wenwen15,Chen Xiaochen15,Liu Chunyu15,Honiball John Robert4,Li Bing3,Ren Youliang67,Chu Lei6,Luo Xuegang2,Pan Haobo15ORCID,Cui Xu15ORCID

Affiliation:

1. Shenzhen Key Laboratory of Marine Biomedical Materials, CAS-HK Joint Lab of Biomaterials, The Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, P. R. China

2. Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education and Tianjin, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, P. R. China

3. Department of Orthopedics, Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Worker’s Hospital, Liuzhou 545000, Guangxi, P. R. China

4. Department of Orthopaedics & Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR 999077, P. R. China

5. Shenzhen Healthemes Biotechnology Co., Ltd., Shenzhen 518055, Guangdong, P. R. China

6. Department of Orthopaedics, Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, P. R. China

7. Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, United States

Funder

National Key Research and Development Program of China

Science and Technology Foundation of Shenzhen City

Natural Science Foundation of Chongqing Municipality

Natural Science Foundation of Guangxi Zhuang Autonomous Region

National Natural Science Foundation of China

Shenzhen Medical Research Foundation

Publisher

American Chemical Society (ACS)

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