A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor

Author:

MacLeod A. Kenneth1,Zang Tuo1,Riches Zoe1,Henderson Colin J.1,Wolf C. Roland1,Huang Jeffrey T.-J.1

Affiliation:

1. Jacqui Wood Cancer Centre, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, James Arrott Drive, Dundee DD1 9SY, Scotland

Funder

Cancer Research UK

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Reference51 articles.

1. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm292362.pdf.

2. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2012/07/WC500129606.pdf.

3. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

4. Is Proteomics the New Genomics?

5. Comparison of Proteomic and Genomic Analyses of the Human Breast Cancer Cell Line T47D and the Antiestrogen-resistant Derivative T47D-r

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