Synthesis of 1,N6-Ethano-2‘-deoxyadenosine, a Metabolic Product of 1,3-Bis(2-chloroethyl)nitrosourea, and Its Incorporation into Oligomeric DNA-Reference-Cited by-同舟云学术

Synthesis of 1,N6-Ethano-2‘-deoxyadenosine, a Metabolic Product of 1,3-Bis(2-chloroethyl)nitrosourea, and Its Incorporation into Oligomeric DNA

Published:1998-06-01 Issue:13 Volume:63 Page:4385-4389
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Maruenda H.¹,Chenna A.¹,Liem L.-K.¹,Singer B.¹

Affiliation:

1. Donner Laboratory, Lawrence Berkeley National Laboratory, University of California, Berkeley, California 94720

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo980170i

Reference18 articles.

1. DNA alkylation by the haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removal

2. Singer, B.; Holbrook, S. R.; Fraenkel-Conrat, H.; Kusmierek, J. T. InThe Role of Cyclic Nucleic Acid Adducts in Carcinogenesis and Mutagenesis; Singer, B., Bartsch, H., Eds.; IARC Scientific Publication, Oxford University Press: New York, 1986; pp 45−58.

3. Structure-activity relations of (2-chloroethyl)nitrosoureas. 2. Kinetic evidence of a novel mechanism for the cytotoxically important DNA cross-linking reactions of (2-chloroethyl)nitrosoureas

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