Exploring Mutation-Driven Changes in the ATP-ADP Conformational Cycle of Human Hsp70 by All-Atom MD Adaptive Sampling-Reference-Cited by-同舟云学术

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Exploring Mutation-Driven Changes in the ATP-ADP Conformational Cycle of Human Hsp70 by All-Atom MD Adaptive Sampling

Published:2024-08-02 Issue:32 Volume:128 Page:7770-7780
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Rinaldi Silvia¹^ORCID,Colombo Giorgio²,Morra Giulia³^ORCID

Affiliation:

1. Institute for the Chemistry of Organometallic Compounds (ICCOM)─National Research Council (CNR), Via Madonna del Piano, 10, Sesto Fiorentino, Firenze 50019, Italy

2. Department of Chemistry, University of Pavia Via Taramelli 12, Pavia 27100, Italy

3. Institute of Chemical Sciences and Technologies (SCITEC)─National Research Council (CNR), Via Mario Bianco 9, Milano 20131, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Ministero dell'Universit? e della Ricerca

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.4c03603

Reference48 articles.

1. Hsp70 chaperones: Cellular functions and molecular mechanism

2. The Hsp70 chaperone network

3. Protein rescue from aggregates by powerful molecular chaperone machines

4. Function, Therapeutic Potential, and Inhibition of Hsp70 Chaperones

5. Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases

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