Role of Asp190 in the Phosphorylation of the Antibiotic Kanamycin Catalyzed by the Aminoglycoside Phosphotransferase Enzyme: A Combined QM:QM and MD Study
Author:
Affiliation:
1. Chemistry Department, Memorial University, St. John’s, Newfoundland and Labrador A1B 3X7, Canada
2. Department of Chemistry, University Institute of Engineering & Technology, Chhatrapati Shahu Ji Maharaj University, Kanpur 208024, India
Funder
Memorial University of Newfoundland
Science and Engineering Research Board
Shastri Indo-Canadian Institute
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.0c01604
Reference53 articles.
1. Chan, M. Antimicrobial resistance: no action today, no cure tomorrow. http://www.who.int/dg/speeches/2011/WHD_20110407/en/.
2. Plant bacteria thrive in storm clouds
3. Destination of aminoglycoside antibiotics in the ‘post-antibiotic era’
4. Aminoglycoside Antibiotics in the 21st Century
5. The Future of Aminoglycosides: The End or Renaissance?
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